DVI News and Events
July 10, 2014
  Please click here for the Dengue Vaccine Initiative (DVI) full statement. Today, July 10, Sanofi Pasteur published in The Lancet the results of the first of two Phase 3 clinical trials for its dengue vaccine candidate — a live attenuated chimeric tetravalent vaccine. The study is a randomized, observer-blind, placebo-controlled multicenter trial involving 10,275 children aged 2 to 14 years in Indonesia, Malaysia, the Philippines, Thailand and Vietnam. An Initial Examination of...
Topics:
May 13, 2014
  The Latest. Monday, April 28, opened a new chapter for dengue vaccine development. For the first time ever, a large-scale, late-stage (Phase 3) study of a dengue vaccine candidate was completed, as the French pharmaceutical company, Sanofi Pasteur, announced in a press release. Coinciding with World Immunization Week, the update has brought more excitement to this dynamic field. According to Sanofi, preliminary results of the Phase 3 trial conducted in 10,000 children in five Asian...
Topics:
May 02, 2014
  With the slogan “Immunization for a healthy future. Know, Check, Protect” WHO reminds us this week that vaccines prevent 2-3 million deaths each year. Just imagine this: 2 to 3 million lives. This equals the populations of countries like Mongolia or Botswana.   As we celebrate the contribution of vaccines to public health, World Immunization Week also gives us the opportunity to appreciate and reflect on ongoing innovations in the field. The development of a dengue...
Topics:
December 20, 2013
It's been a big year for dengue, and with the start of 2014 near we thought that we'd reflect on all that's happened in 2013.  This story originally appeared in our December Newsletter, and you can check out the full Newsletter here. 2013 opened with the release of the WHO’s Second Report on Neglected Tropical Diseases in January, a report that ranked dengue as the fastest spreading vector-borne viral disease in the world.  This report, which called on the world to...
Topics:
October 17, 2013
  Dr. Duane Gubler is professor and Program Director for Emerging Infectious Diseases at the Duke-NUS Graduate Medical School, Singapore. Dr. Gubler is also an Adjunct Professor at his alma mater, Johns Hopkins University Bloomberg School of Public Health. He has spent his entire career working on tropical infectious diseases with an emphasis on dengue and dengue haemorrhagic fever/severe dengue.  He has published extensively in the area of dengue and other vector-borne infectious...
Topics:
September 27, 2013
Delhi is once again facing a near outbreak of dengue. The official count for 2013 stands at 1,355 cases, with 1,193 of those occurring in September. Dengue cases are also being reported elsewhere in the country, and Google dengue trends shows a dramatic rise for India in the past month. The official figures, though, are widely recognized to be an underreporting of the situation.  A recent New York Times article explores the growing dengue numbers in Delhi, and the widespread underreporting...
Topics:
August 21, 2013
  While dengue outbreaks in Singapore and Thailand have recently captured headlines, the Western hemisphere has seen a steep uptick in cases compared to 2012. Central America is already on track to soon pass the total number of cases for all of last year. The number of cases reported is alarming – and even worse -- new cases are occurring in regions that have not seen dengue before.    This week the number of dengue cases in Costa Rica’s ongoing outbreak reportedly...
Topics:
July 22, 2013
This blog was originally posted on IVAC's blog. By Dr. Dagna Constenla and Samantha Clark For many people throughout the world, the bite of a mosquito is nothing more than a common annoyance. But for individuals living in dengue endemic countries such an annoyance can quickly turn into a life threatening condition. Patients who get sick with dengue fever often experience excruciating headaches, skin rash, and debilitating muscle and joint pains. In severe cases, it can lead to circulatory...
Topics:
July 09, 2013
  The following is from the latest DVI Newsletter.  Find the full newsletter here. In April, a new study published in Nature estimated that there were nearly 400 million dengue infections in 2010. This new figure is more than three times as much as in the official estimates by the World Health Organization (WHO) of 50-100 million dengue infections a year.  DVI spoke with Professor Simon Hay, Dr. Jane Messina and Oliver Brady, authors on “The global distribution and burden...
Topics:
June 19, 2013
When we last wrote about Singapore’s dengue outbreak just over a month ago, the total number of cases had already reached over 6,000 – more than the number of cases in all of 2012.  Last week, Singapore broke the 10,000 mark. The country also set a new record for the weekly number of new cases, with 756 infections reported for the week of May 26 to June 1.  To date there have been two deaths reported.  All of this, while the high season for dengue in Singapore has...
Topics:
Title | Date